Welcome to the 77th issue of HIV This Week! In this issue, we cover stigma (stigma towards people living with HIV in the USA: time to move from studying stigma to learning how to foster resilience and solidarity; Community popular opinion leaders and HIV-related stigma reduction in China), treatment (the details on DART you have [...]
Meta-analysis of health and demographic correlates of stigma towards people living with HIV.
Logie C, Gadalla TM. AIDS Care. 2009 2:742-53.
HIV-related stigma may negatively impact the health, quality of life, social support and well-being of people living with HIV (PLHIV). Previous studies have used diverse samples and a multitude of measurement instruments to examine [...]
Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomised non-inferiority trial.
DART Trial Team. The Lancet, Early Online Publication, 9 December 2009 [Epub ahead of print]
HIV antiretroviral therapy (ART) is often managed without routine laboratory monitoring in Africa; however, the effect of this approach is unknown. This trial [...]
Accuracy of serological assays for detection of recent infection with HIV and estimation of population incidence: a systematic review.
Guy R, Gold J, Calleja JM, Kim AA, Parekh B, Busch M, Rehle T, Hargrove J, Remis RS, Kaldor JM; WHO Working Group on HIV Incidence Assays. Lancet Infect Dis. 2009 9:747-59.
The authors systematically reviewed [...]
Home testing for HIV infection in resource-limited settings.
Ganguli I, Bassett IV, Dong KL, Walensky RP. Curr HIV/AIDS Rep. 2009;6:217-23.
Among an estimated 33 million individuals who are infected with HIV worldwide, only 10% are aware of their status. HIV testing is the cornerstone to preventing further transmission and to caring for those infected, particularly [...]
Effectiveness of paediatric antiretroviral therapy in resource-limited settings: a systematic review and meta-analysis.
Ciaranello AL, Chang Y, Margulis AV, Bernstein A, Bassett IV, Losina E, Walensky RP. Clin Infect Dis. 2009;49:1915-27.
Responses to antiretroviral therapy (ART) among human immunodeficiency virus (HIV)-infected children in resource-limited settings have recently been reported, but outcomes vary. The authors sought [...]
Structural barriers and human rights related to HIV prevention and treatment in Zimbabwe.
Amon JJ, Kasambala T. Glob Public Health. 2009;4:528-45.
There has long been recognition that individual risk factors can only partially explain vulnerability to HIV infection, and that a broader range of socioeconomic, cultural and political factors must be taken into account. More [...]
Trends in HIV Prevalence, Estimated HIV Incidence, and Risk Behaviour Among Men Who Have Sex With Men in Bangkok, Thailand, 2003-2007.
van Griensven F, Varangrat A, Wimonsate W, Tanpradech S, Kladsawad K, Chemnasiri T, Suksripanich O, Phanuphak P, Mock P, Kanggarnrua K, McNicholl J, Plipat T. J Acquir Immune Defic Syndr. 2009 No. [Epub ahead [...]
Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1.
Benlahrech A, Harris J, Meiser A, Papagatsias T, Hornig J, Hayes P, Lieber A, Athanasopoulos T, Bachy V, Csomor E, Daniels R, Fisher K, Gotch F, Seymour L, Logan K, Barbagallo R, Klavinskis L, [...]
The impact of HIV scale-up on health systems: A priority research agenda.
Rabkin M, El-Sadr WM, De Cock KM; Bellagio HIV/Health Systems Working Group1. J Acquir Immune Defic Syndr. 2009 Nov;52 Suppl 1:S6-11.
Collaborators: Abrams E, Cahn P, Coovadia H, De Cock KM, Dybul M, El-Sadr W, Freywhot S, Isbell M, Levine R, Melaku Z, [...]
Two Distinct Epidemics: The Rise of HIV-1 and Decline of HIV-2 Infection Between 1990 and 2007 in Rural Guinea-Bissau.
van Tienen C, van der Loeff MS, Zaman SM, Vincent T, Sarge-Njie R, Peterson I, Leligdowicz A, Jaye A, Rowland-Jones S, Aaby P, Whittle H. J Acquir Immune Defic Syndr. 2009 Oct. [Epub ahead of print]
This [...]
How can we support the use of systematic reviews in policymaking?
Lavis JN. PLoS Med. 2009;6:e1000141. Epub 2009 Nov 17.
Policymakers need many types of research evidence—synthesized and packaged for them —and the use of this evidence supported in multiple complementary ways. Stakeholders who seek to influence the policymaking process have the same requirements. Policymakers [...]
