HIV This Week

Welcome to the thirty-eighth issue of HIV This Week!  In this issue, we cover research ethics (can and should adolescents in South Africa be the subjects of HIV vaccine trials and what would it take?; ever heard of the CIOMS Guidelines on Ethics of Clinical Trials – now you have!), stigmatisation (perceived stigma from health care providers turns people away from care in Los Angeles County), basic science (chemokine receptor genetic polymorphisms may be important for disease progression and not just for susceptibility to HIV in the first place), injecting drug use (public injecting in Vancouver – schedules at the supervised injection facility may be a contributing factor), HIV testing (rural community-based VCT in Chiang Mai Province, northern Thailand; increased sexual risk after a negative HIV result in Manicaland, Zimbabwe), sexual transmission and behaviour (HIV risk and protective factors in uncircumcised young men in Kisumu, Kenya; modelling shows not only that serosorting may not protect, it can potentially increase HIV transmission), pre-exposure prophylaxis (modelling the impact before any trial results – an interesting exercise), treatment (genotypic drug resistance mutations in Ivory Coast – time to think second line drug prices; quality of life among rural Ugandans on antiretroviral therapy; CD4 cell count testing and improved prognosis in asymptomatic HIV patients in rural Rakai district, Uganda; treatment interruptions and other causes of disease progression among injecting drug users on antiretroviral treatment in Baltimore; survival benefit after changes in the AIDS case definition to CD4 count below 350 cells/mm in Sao Paulo State, Brasil), microbicides (an overview of the past, present and future of the search for an effective anti-HIV microbicide).

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Don’t forget that you can find a wealth of information on the HIV epidemic and responses to it at http://www.unaids.org.

For full pdf access of this issue: HIV This Week issue #38